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Thursday, Jul 14 2016

Full Issue

Gene Linked To Alzheimer's Affects Brain Development In Children, Study Finds

The findings, published Wednesday by the journal Neurology, suggest that it may be useful to think of Alzheimer's as a developmental disorder. In other news, drugmakers are teaming up to more quickly develop treatments for the disease.

The gene that makes some people more vulnerable to Alzheimer鈥檚 disease as adults also affects the brain development and mental abilities of children, a new study shows. Researchers who examined brain scans of 1,187 kids and teens found distinct patterns in the size and structure of the cortex, hippocampus and other important structures. These patterns were linked with different versions of a gene known as APOE, which may play a role in up to 25% of Alzheimer鈥檚 cases. (Kaplan, 7/13)

Five drug makers, including Cambridge-based Biogen Inc., are banding together with academic scientists to form a research consortium aimed at speeding development of therapies for Alzheimer鈥檚, a neurological disorder that has stubbornly eluded treatments. The new group, which will be formally launched Thursday night at an event at Massachusetts General Hospital, is called the Massachusetts Center for Alzheimer Therapeutic Science, or MassCATS. It will be based at a Mass. General research center. (Weisman, 7/14)

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