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Morning Briefing

Summaries of health policy coverage from major news organizations

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Monday, Sep 16 2019

Full Issue

Cluster Of Autism Cases All Linked To Same Sperm Donor Could Provide Genetic Insight Into Diagnosis

Donor H898 was blond and blue-eyed, 6-foot-1, 240 pounds, and appeared to be smart and accomplished. Now it turns out that many of the kids conceived with his sperm have autism. Experts are intrigued by the genetic clues the cluster of cases could offer. In other public health news: gene-editing, hospital care, maternal mistreatment, lead levels in water, heart attacks in women, and more.

Danielle Rizzo鈥檚 son is screaming. He is planted in the middle of the lobby of his elementary school, clinging to rainbow-colored blocks as she gently explains that she is here 鈥 off schedule, in the middle of the day 鈥 to take him to a doctor鈥檚 appointment. But the first-grader is not listening. 鈥淗appy Meal,鈥 he repeats over and over again. 鈥淗appy Meal!鈥 His little brother, who is also going to the appointment, is nearby, not moving. Rizzo is relieved that the two of them are not melting down at the same time, which happens all too often, and firmly guides them out the door. (Cha, 9/14)

Amid last year鈥檚 backlash against the birth of the world鈥檚 first genetically edited babies, some experts preached prudence: Editing the genomes of embryos, they argued, could one day 鈥渃ure鈥 people of diseases before they鈥檙e even born. But there is another, less-discussed potential application of editing an embryo: tweaking its DNA to help save someone who is already alive. (Joseph, 9/16)

The Hospital for Special Care in New Britain, Conn., had 10 patients in its close observation unit on a recent afternoon. Visitors could hear the steady ping of pulse monitors and the hum of ventilators. The hospital carefully designed these curtained cubicles to include windows, so that patients can distinguish day from night. It also placed soothing artwork 鈥 ocean scenes and landscapes 鈥 on the ceilings for those who can鈥檛 turn over and look outside. (Span, 9/13)

The culture of obstetrics as it has traditionally been practiced doesn鈥檛 help: women on their backs, legs spread, while physicians use tools on their bodies.Given these conditions, it may come as no surprise that a new survey of 2,700 US women published in June found that nearly 1 in 6 pregnant, laboring, and postpartum women experienced mistreatment by medical providers. For women who delivered in a hospital, as opposed to a freestanding birth center or at home, that figure climbed to nearly 1 in 3. (Somerstein, 9/13)

A drinking water crisis in New Jersey's biggest city is bringing new attention to an old problem: Millions of homes across the U.S. get their water through pipes made of toxic lead, which can leach out and poison children if the water isn't treated with the right mix of chemicals. Replacing those lead pipes is a daunting task for cities and public water systems because of the expense involved 鈥 and the difficulty of even finding out where all those pipes are. (Porter and Catalini, 9/13)

Axel Ullrich, who directs the department of molecular biology at the Max Planck Institute of Biochemistry, shared a stake in this year鈥檚 $250,000 Lasker Award for his work on Herceptin, a treatment for breast cancer. Ullrich鈥檚 Lasker-DeBakey Clinical Medical Research Award, announced last week, will join a slew of coveted honors in biomedicine that already sit on his mantel, including the King Faisal Prize, the Warren Alpert Foundation Prize, the Wolf Prize and others.聽The Lasker is sometimes a harbinger of an even bigger prize, the Nobel. But Ullrich is in select company for another reason as well 鈥 he鈥檚 one of several world-class scientists who鈥檝e won major awards, including the Nobel, but also have had to retract some of their work. (Oransky and Marcus, 9/16)

Men's symptoms tend to center on crushing chest pain, traditional thinking goes 鈥 that's long been known as "typical angina" 鈥 while women are more likely to have other or additional symptoms: fatigue, nausea, sweating, pain in the arm, shoulder or back -- that's known as "atypical angina." But new Boston-based research used artificial intelligence to analyze how hundreds of patients described their symptoms in their own words, and it challenges that dogma. (Goldberg, 9/13)

Scientists are pursuing the first medicines to treat hearing loss. Today鈥檚 principal treatments鈥攈earing aids and electronic devices called cochlear implants鈥攈elp many people who have suffered damage to their ears caused by aging, noise, genetics or drugs. But neither of those treatments cures or counters the biological causes of hearing loss. By contrast, several experimental new drugs aim to do just that. (Gormley, 9/15)

When Anne Madison could no longer hear her microwave beep, she assumed that her appliance needed repair. In fact, the machine worked well, but her confusion foreshadowed a frustrating struggle: a long and lonely battle with hearing loss. Madison didn't bother going to a doctor after the microwave incident. She knew that hearing aids were so expensive that she could never afford them. So she decided to deal with the hassles of hearing impairment on her own and "just kind of pulled up my socks." (Sharpe, 9/12)

Bridget Desmukes was surprised when her OB-GYN recommended low-dose aspirin at her first prenatal appointment this past spring. She knew about daily low-dose aspirin being prescribed to people recovering from a heart attack or stroke. But for pregnant women? In a past pregnancy, Desmukes had developed preeclampsia, a potentially serious complication that involves high blood pressure. A small amount of daily aspirin, it turns out, can significantly cut the risk of developing preeclampsia in pregnancy. (Simmons-Duffin, 9/16)

A growing body of research suggests that skin may play a bigger role in fueling chronic disease and age-related illness than previously understood. A recent study in animals found that skin, when attacked, produces enough of an inflammatory substance called cytokines to affect not only the skin but the rest of the body, as well. And body-wide inflammation, when it persists, is thought to contribute to and accelerate chronic conditions such as heart disease and lupus. (Wang, 9/15)

Late one morning in June, L.J.鈥檚 husband got a distressed call from one of his wife鈥檚 colleagues. 鈥淵ou鈥檇 better come here right away. Your wife is acting weird,鈥 the colleague said. Ms. J., who had just returned from a doctor visit during which she underwent a minor painful procedure, kept asking her colleague for a password despite being told each time that there was none. (Brody, 9/16)

Ready or not, here they come: Scientists who played hide and seek with rats found that their furry subjects seemed to love the game 鈥 and they were remarkably good at it. The unconventional experiment, described in Friday鈥檚 edition of the journal Science, sheds light on the sophisticated sense of play in these tiny rodents and the complex mechanisms at work in their brains. It also hints at the evolutionary usefulness of this type of play. (Khan, 9/13)

This is part of the Morning Briefing, a summary of health policy coverage from major news organizations. Sign up for an email subscription.
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